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A simple method of continuous passage of a human tumor through immunocompetent mice

✍ Scribed by A. Lokshin; V. I. Ryabkova; V. K. Sokolova

Publisher
Springer US
Year
1992
Tongue
English
Weight
570 KB
Volume
113
Category
Article
ISSN
0007-4888

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## Abstract Hep 2/5 cells, a clone of HeLa which expresses both placental‐type alkaline phosphatase and fetal intestinal alkaline phosphatase (ALP), were grown as solid tumors in nude mice. Analysis of ALP isozymes present in tumor specimens excised at intervals over a 52‐day period showed that lev