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A simple method for the synthesis of some 1,2-diazocines

✍ Scribed by Makhluf J. Haddadin; Bushra J. Agha; M.Samer Salka


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
155 KB
Volume
25
Category
Article
ISSN
0040-4039

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A simple method for the synthesis of 2β€²-
✍ Morten GrΓΈtli; Mark Douglas; Barbro Beijer; Ramon Eritja; Brian Sproat πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 226 KB

A new synthetic route has been devised for the preparation of 2'-O-alkyl guanosine derivatives. Utilizing a strategy of minimal protection, the alkylation was performed on partly protected guanosine using an alkyl halide and a sterically hindered strong organic base.