The absolute configuration of the (À)-enantiomer of mirtazapine was determined by means of vibrational circular dichroism (VCD). The observed VCD of (À)-mirtazapine showed excellent correlation with the calculated VCD of the (R)-enantiomer. This is in agreement with the absolute configuration as det
✦ LIBER ✦
A simple circular dichroism method for the determination of the absolute configuration of allylic amines
✍ Scribed by P Skowronek; J Gawroński
- Book ID
- 108379684
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 87 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Vibrational circular dichroism (VCD) measurements and density functional theory (DFT) calculations were used to obtain the first definitive assignment of the absolute configuration for the polyphenolic binaphpthyl dialdehyde gossypol and a determination of the solution conformation in C