## Abstract The [2+2+2] cyclotrimerization of 1,7,9,15‐hexadecatetrayne with nitriles catalyzed by dicarbonylcyclopentadienylcobalt(I) opened a new pathway for the synthesis of __C__~2~‐symmetrical bis(tetrahydroisoquinolines) that were used as starting material for the preparation of axially chira
A Simple Approach to Unsymmetric Atropoisomeric Bipyridine N,N′-Dioxides and Their Application in Enantioselective Allylation of Aldehydes
✍ Scribed by Radim Hrdina; Irena Valterová; Jana Hodačová; Ivana Císařová; Martin Kotora
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 102 KB
- Volume
- 349
- Category
- Article
- ISSN
- 1615-4150
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## Abstract magnified image Unsymmetrically 3,3′‐substituted axially chiral bis(tetrahydroisoquinoline) __N,N′‐__dioxides can be prepared in just three steps. They exhibit unique catalytic activity (turnover frequency, enantioselectivity, substrate scope) in the asymmetric allylation of aromatic a
## Abstract Palladium‐catalyzed cross‐coupling of bipyridine __N,N′__‐dioxide 6,6′‐dichloride (__R__~__nap__~__,R__~__pyr__~)‐**1** with the aryl Grignard reagents opened a new approach to axially chiral bipyridine __N,N′‐__dioxides (__R__)‐**2** bearing a variety of aryl groups at the 6 and 6′ pos