Novel Chiral Pyridine N-Oxide Ligands and Their Application in the Enantioselective Catalytic Reduction of Ketones and the Addition of Diethylzinc to Aldehydes
✍ Scribed by Volker Derdau; Sabine Laschat; Eike Hupe; Wilfried A. König; Ina Dix; Peter G. Jones
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 275 KB
- Volume
- 1999
- Category
- Article
- ISSN
- 1434-1948
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📜 SIMILAR VOLUMES
A new chiral ligand 6, 6'-dihydroxy-5, 5'-biquinoline (BIQOL, 2) was prepared via Cu2+ mediated coupling. The resolution was carried out by separating the corresponding ditrifluomethanesulfonate on chiral column. When applied to the enantioselective addition of diethylzinc to aromatic aldehydes, thi
Several new chiral auxiliaries with differing steric and electronic environments, such as ␣,␣Ј-dimethyl-2,6-pyridinedimethanol, ␣,␣Ј-ditrifluoromethyl-2,6pyridinedimethanol, ␣,␣Ј-dipentafluoroethyl-2,6-pyridinedimethanol, and ␣,␣Ј-diallyl-2,6pyridinedimethanol, have been examined and compared with ␣