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A simple and recyclable copper/DTPA catalyst system for amination of aryl halides with aqueous ammonia in water

✍ Scribed by Yang, Bo; Liao, Lihao; Zeng, Yongheng; Zhu, Xinhai; Wan, Yiqian


Book ID
121686861
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
320 KB
Volume
45
Category
Article
ISSN
1566-7367

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## Abstract The __N^2^,N^2^β€²__‐diisopropyloxalohydrazide/CuO system efficiently catalyzed the direct amination of aryl bromides andiodides with aqueous ammonia in water at 60 Β°C in 24 h or at 120 Β°C in only 20–30 min. Both activated and unactivated aryl and heteroaryl bromides and iodides were read

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## Abstract The easy availability of the ligand, the commercially available cheap copper source, the use of a green solvent and aqueous ammonia as the readily available nitrogen source are features of this protocol.