𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A short synthesis of the marine bioactive metabolite (+/−) girolline

✍ Scribed by S. Marchais; A. Al Mourabit; A. Ahond; C. Poupat; P. Potier

Book ID
104260066
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
181 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new 2 step synthesis of (+/-) girolline 1 starting from the easily available o~-chloro-13aminoaldehyde 4 and 2-aminoimidazole 5 is described. The reaction of 4 with 5, followed by deprotection, affords the threo diastereoisomer.

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