𝔖 Bobbio Scriptorium
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A short synthesis of (±)-decarestrictine L

✍ Scribed by J.Stephen Clark; Gavin A. Whitlock


Book ID
104214656
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
153 KB
Volume
35
Category
Article
ISSN
0040-4039

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Synthesis of (+)-decarestrictine L
✍ Julie M. Lukesh; William A. Donaldson 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 251 KB

A synthesis of (+)-decarestrictine L 1, a cholesterol biosynthesis inhibitory metabolite isolated from Penicillium simplicissimum, is described. Beginning from tri-O-acetyl-D-glucal, alkylation with trimethylaluminum introduced the axial methyl group at C-2 in a stereoselective fashion. Chain extens