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A Short Synthesis of (.+-.)-Cytisine.

✍ Scribed by Candice Botuha; Carl M. S. Galley; Timothy Gallagher


Publisher
John Wiley and Sons
Year
2004
Weight
9 KB
Volume
35
Category
Article
ISSN
0931-7597

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Three different radical reactions were used in a short total synthesis of (Β±)-matrine (1). Two of the four six-membered rings and four new bonds were created in one radical cascade involving intermolecular addition followed by two successive cyclizations and transfer of a xanthate group.