A practical synthesis of (5R)and (5S)-[5-3H]-L-ornithine is described. The key steps in the synthesis are the reduction of vonnyl-3H]J-hexenal with S-or R-Alpine Borane to (1R)and (1s)-[ 1-3H]J-hexen-l-ol and the use of the Evans electrophilic azidation of c h i d h i d e enolates to introduce the a
A Short and Efficient Synthesis of l -5,5,5,5‘,5‘,5‘-hexafluoroleucine from N -Cbz- l -Serine
✍ Scribed by Anderson, James T.; Toogood, Peter L.; Marsh, E. Neil G.
- Book ID
- 121505613
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 40 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1523-7060
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5-Thio-L-fucopyranose tetraacetate was synthesized in 11 steps from 5-O-trityl-D-arabinofuranose or D-arabinose diethyl dithioacetal by one-carbon elongation at C-5. Highly diastereoselective addition of MeLi in ether to a 1,2-O-isopropylidene-[J-D-arabino-pentodialdo-l,4-furanose derivative was ach