A new method for separating cyclic AMP f
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Asru K. Sinha; Robert W. Colman
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Article
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1981
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Elsevier Science
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English
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A new method for assay of cyclic AMP phosphodiesterase (EC 3.1.4.17) has been developed based on the observation that a mixture of cyclic AMP and AMP can be resolved on a column of florisil (activated magnesium silicate) at pH 7.0. The cyclic nucleotide is retained by the silicate and the AMP which