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A sensitive method for simultaneous determination of histamine and noradrenaline with high-performance liquid chromatography/electrochemistry

✍ Scribed by Han Xinqiang; Man M. Vohra

Book ID
116097168
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
798 KB
Volume
25
Category
Article
ISSN
0160-5402

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Simultaneous determination of histamine and NΟ„-methylhistamine with high-performance liquid chromatography using electrochemical detection
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We have developed a liquid chromatographic method which uses electrochemical detection for the simultaneous quantitation of histamine and N'-methylhistamine in rat brain. The amines are derivatized with the water-soluble Bolton-Hunter reagent (sulfo B-H). Perchloric acid extracts of rat brains are c