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A sensitive fluorescence assay for quantitation of fludarabine and metabolites in biological fluids

✍ Scribed by Annette Kemena; Mechelle Fernandez; John Bauman; Michael Keating; William Plunkett


Book ID
115827093
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
907 KB
Volume
200
Category
Article
ISSN
0009-8981

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A high performance liquid chromatography method is described for measuring Ifosfamide (I) in human serum. This involves solvent extraction, reverse phase HPLC and UV detection at 190 nm. Standard curves of peak height x detector sensitivity versus I concentration in serum were linear with a lower li