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A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses

✍ Scribed by Shahbazi, Shandiz; Peer, Cody J.; Polizzotto, Mark N.; Uldrick, Thomas S.; Roth, Jeffrey; Wyvill, Kathleen M.; Aleman, Karen; Zeldis, Jerome B.; Yarchoan, Robert; Figg, William D.

Book ID
122166705
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
775 KB
Volume
92
Category
Article
ISSN
0731-7085

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A new HPLC method with fluorescence dete
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## Abstract A sensitive, selective, simple and fast HPLC method based on the formation of derivative with fluorescamine was developed for the determination of memantine (ME) in human plasma. Separation was achieved on a CN column (200 mmΓ—4.6 mm) using acetonitrile–10 mM orthophosphoric acid contain