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A selective inhibitor of matrix metalloproteinases inhibits the migration of isolated osteoclasts by increasing the life span of podosomes

โœ Scribed by Tetsuya Goto; Hidefumi Maeda; Teruo Tanaka


Publisher
Springer
Year
2002
Tongue
English
Weight
298 KB
Volume
20
Category
Article
ISSN
0914-8779

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The synthetic matrix metalloproteinase inhibitor batimastat was tested for its ability to inhibit growth and metastatic spread of the B16-BL6 murine melanoma in syngeneic C57BL/6N mice. lntraperitoneal administration of batimastat resulted in a significant inhibition in the number of lung colonies p