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A screening procedure to evaluate the anticoagulant activity and the kinetic behaviour of direct thrombin inhibitors

✍ Scribed by Alain Rupin; Philippe Mennecier; Guillaume de Nanteuil; Michel Laubie; Tony J. Verbeuren


Book ID
116086857
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
639 KB
Volume
78
Category
Article
ISSN
0049-3848

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πŸ“œ SIMILAR VOLUMES


Solid phase chemistry approach to the SA
✍ Mary George Johnson; Duane D. Bronson; Jan E. Gillespie; Donetta S. Gifford-Moor πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 699 KB

A solid phase chemistry approach utilizing Mitsunobu chemistry, amine functionalization, and parallel purification was used to produce a diverse library of benzothiophene analogs. These analogs were used to advance the SAR of this class of molecules and give new directions for future studies.