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A screening method of SH2 domain ligands and blockers using a solid phase binding

✍ Scribed by Woo Suk Koh; Sun Young Yoon; Eun Kyung Lee; Byoung Mok Kwon; Jae Won Kim; Mi Young Han

Book ID
117468587
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
181 KB
Volume
120
Category
Article
ISSN
0304-3835

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## Abstract A new methodology for the rapid assessment of affinity ligands synthesized by combinatorial solid‐phase chemistry is reported. This screening strategy utilizes the target protein conjugated to FITC, and represents an almost universal technique for the preliminary screening of solid‐phas