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A route to 3H-1,2-diazepines by the 1,7-electrocyclisation of ?,??,?-unsaturated diazo-compounds

โœ Scribed by Robertson, Ian R.; Sharp, John T.


Book ID
121458547
Publisher
The Royal Society of Chemistry
Year
1983
Tongue
English
Weight
213 KB
Volume
0
Category
Article
ISSN
0022-4936

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Asymmetric induction in the 1,7 ring clo
โœ Alexander J. Blake; Mervyn Harding; John T. Sharp ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 248 KB

In the cyclisation of the diazo-compound (7) to give the diastereomerit pair of lH-2,3\_benzodiazepines (8) and ( 9), alkoxy groups, when present as the medium sized group M, show the opposite effect in promoting face selectivity to that of alkyl groups and the alkoxide ion. Thus when M=OMe the ( 8