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A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

✍ Scribed by C.Erik Hack; Gert-Jan Wolbink; Caspar Schalkwijk; Han Speijer; Willem Th. Hermens; Henk van den Bosch

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
323 KB
Volume
18
Category
Article
ISSN
0167-5699

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✦ Synopsis

The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

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