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A role for pore-forming proteins in the pathogenesis by parasites?

โœ Scribed by D.M. Ojcius; J. Ding-E Young

Book ID
119139685
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
611 KB
Volume
6
Category
Article
ISSN
0169-4758

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Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid mem