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A Role for Nuclear Factor Kappa B/Rel Transcription Factors in the Regulation of the Recombinase Activator Genes

✍ Scribed by Laurent Verkoczy; Djemel Aït-Azzouzene; Patrick Skog; Annica Märtensson; Julie Lang; Bao Duong; David Nemazee

Book ID
116570431
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
875 KB
Volume
22
Category
Article
ISSN
1074-7613

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The activation of B and T cells by a wide range of stimuli can rapidly induce specific gene expression via a mechanism that promotes the nuclear translocation of different Rel/nuclear factor-kappa B (NF-kappa B) transcription factors which are normally resident in the cytoplasm. Recent findings high