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A role for mitogen-activated protein kinase and Ets-1 in the induction of interleukin-10 transcription by human immunodeficiency virus-1 Tat

✍ Scribed by James C. B. Li; Allan S. Y. Lau


Book ID
108782077
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
672 KB
Volume
121
Category
Article
ISSN
0019-2805

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)