A Robust Test for Two-Stage Design in Genome-Wide Association Studies
✍ Scribed by Minjung Kwak; Jungnam Joo; Gang Zheng
- Book ID
- 109224114
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 174 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0006-341X
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📜 SIMILAR VOLUMES
## Abstract Genome‐wide association (GWA) studies require genotyping hundreds of thousands of markers on thousands of subjects, and are expensive at current genotyping costs. To conserve resources, many GWA studies are adopting a staged design in which a proportion of the available samples are geno
## Abstract The much‐anticipated fixed‐array, genome‐wide SNP genotyping technologies make large‐scale genome‐wide association scans now possible for large numbers of subjects. In this paper we reconsider the problem (Satagopan and Elston [2003] Genet Epidemiol 25:149–157) of optimizing a two‐stage