𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A robust statistical method for case-control association testing with copy number variation

✍ Scribed by Barnes, Chris; Plagnol, Vincent; Fitzgerald, Tomas; Redon, Richard; Marchini, Jonathan; Clayton, David; Hurles, Matthew E


Book ID
109914300
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
527 KB
Volume
40
Category
Article
ISSN
1061-4036

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Robust Tests for Candidate-Gene Associat
✍ Gang Zheng; Zehua Chen 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 1 views

## Abstract In case‐parents trios design, the association between a multi‐allelic candidate‐gene and a disease can be detected by using maximum of score tests (max‐score) when the mode of inheritance is known. We apply the maximum of the max‐score statistics and the maximum of likelihood ratio stat

What's the best statistic for a simple t
✍ Chia-Ling Kuo; Eleanor Feingold 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

## Abstract Genome‐wide genetic association studies typically start with univariate statistical tests of each marker. In principle, this single‐SNP scanning is statistically straightforward—the testing is done with standard methods (e.g. χ^2^ tests, regression) that have been well studied for decad