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A risk index for the prediction of the incidence of non-A, non-B posttransfusion hepatitis in open-heart surgery patients

โœ Scribed by Dr Yasuko Nagatsuka; Hitoshi Ohori; Atsushi Kanno; Yasuyuki Abe; Takao Togoh; Nakao Ishida

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
698 KB
Volume
12
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

โœฆ Synopsis

Risk factors related to the occurrence of non-A, non-B posttransfusion hepatitis (PTH) were statistically analyzed in 204 patients (115 adults and 89 children) who received blood transfusion and extracorporeal circulation during open-heart surgery. The PTH incidence, irrespective of age or body weight, was affected by both transfusion volume and circulation time, ie, the incidence increased cumulatively with the increment of these two variables. Based upon such statistical analysis, a "PTH-risk index," from which one can objectively predict the probability of PTH, was devised by the summation of standardized transfusion volumes (Vs) and circulation time (Ts). As a result, a high correlation between the obtained PTH-risk index and actual incidence was found. The obtained straight regression line between PTH-risk index and the actual incidence rate enabled us to predict the incidence of PTH in open-heart surgery patients.

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