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A risk factor for relapse in Hodgkin's disease: Female gender?

✍ Scribed by G. M. Jeffery; B. M. Colls; B. A. Robinson; B. M. Fitzharris; C. H. Atkinson


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
542 KB
Volume
7
Category
Article
ISSN
0278-0232

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✦ Synopsis


A retrospective study of 163 patients with Hodgkin's disease treated between 1969 and 1987 was performed to identify adverse prognostic factors. One hundred and thirty-five patients (83 per cent) attained a complete remission and 42 (31 per cent) of these have relapsed (median follow-up-43 months). Using multivariate analysis, no independent factors predicted for the event of relapse. However, analysis of disease-free survival revealed that females fared significantly worse than males (p< 0.05) and this was independent of other prognostic variables. Female sex has not been recognized as an independent prognostic factor predictive of inferior survival and inferior disease-free survival.


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