A Ring-Closing Metathesis Pathway to Flu
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Valeria De Matteis; Floris L. van Delft; JΓΆrg Tiebes; Floris P. J. T. Rutjes
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Article
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2006
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John Wiley and Sons
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English
β 206 KB
## Abstract The synthesis of highly functionalized fluorinated piperidines is described. The key step in this synthesis is a ringβclosing metathesis reaction involving fluorideβsubstituted olefins, which leads to the corresponding cyclic vinyl fluorides. Several sequences to arrive at differently s