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A Ring-Closing Metathesis Pathway to Fluorovinyl-Containing Nitrogen Heterocycles.

✍ Scribed by Valeria De Matteis; Floris L. van Delft; Joerg Tiebes; Floris P. J. T. Rutjes


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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A Ring-Closing Metathesis Pathway to Flu
✍ Valeria De Matteis; Floris L. van Delft; JΓΆrg Tiebes; Floris P. J. T. Rutjes πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 206 KB

## Abstract The synthesis of highly functionalized fluorinated piperidines is described. The key step in this synthesis is a ring‐closing metathesis reaction involving fluoride‐substituted olefins, which leads to the corresponding cyclic vinyl fluorides. Several sequences to arrive at differently s