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A revision of the Biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF

✍ Scribed by Franca Bigi; Silvia Carloni; Bettina Frullanti; Raimondo Maggi; Giovanni Sartori

Book ID: 104261217
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 198 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00424-4

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✦ Synopsis

The reaction of aldehydes, 13-dicarbonyl compounds and urea (Biginelli reaction) has been performed over solid acid catalysis, under solventless conditions or in water affording dihydropyrimidines in good yield and selectivity.

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