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A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer

✍ Scribed by Tuya Pal; Jenny Permuth-Wey; Thomas A. Sellers

Book ID
102105803
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
194 KB
Volume
113
Category
Article
ISSN
0008-543X

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Frequency of mismatch repair deficiency
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## Abstract Loss of mismatch repair (MMR) capacity may represent an important tumor initiating mechanism in ovarian cancer. We conducted a systematic review to analyze the frequency of microsatellite instability (MSI), immunohistochemical (IHC) staining for MMR proteins, and hypermethylation of the