In inducing immunodeficiency in human immunodeficiency virus (HIV)-l infection, a role for the HIV-1 Tat protein has been suggested. In addition to effects on viral transcription, the protein has been ascribed immunosuppressive functions, which were investigated in this study. Proliferation of purif
A review of HIV-1 Tat protein biological effects
β Scribed by A. Pugliese; V. Vidotto; T. Beltramo; S. Petrini; D. Torre
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 64 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1147
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Retroviral transduction of cells is improved upon virus adsorption onto immobilized fibronectin (FN) fragments. Because HIVβ1 Tat possesses the same functional domains that lead to increased transduction efficiency in FN by colocalization of bound virus and cells, we hypo
## Abstract The role of Sp1 in regulating the transβactivating activity of the human immunodeficiency virus type 1 (HIVβ1) Tat protein has not yet been clearly defined. In fact, studies on the physical and functional interaction between Sp1 and Tat have yielded contradictory results. Here we invest