𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A review of current applications of mass spectrometry for biomarker/molecular tracer elucidations

✍ Scribed by Bernd R.T. Simoneit


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
853 KB
Volume
24
Category
Article
ISSN
0277-7037

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Mass spectrometry, especially coupled with gas chromatography or tandem, is the analytical method of choice in elucidations of biomarker compounds present in organic mixtures extracted from geological, environmental, or biological samples. This review describes the biomarker concept; i.e., the precursor natural products to the geological/environmental derivatives, and their application as tracers in the geosphere and ambient environment. The mass spectrometric methods currently utilized for such analyses are reviewed, and typical examples of applications are described with a general key to the literature. Β© 2004 Wiley Periodicals, Inc., Mass Spec Rev 24:719–765, 2005


πŸ“œ SIMILAR VOLUMES


Electron ionization time-of-flight mass
✍ Nasrin Mirsaleh-Kohan, Wesley D.Robertson, and Robert N.Compton πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 817 KB

This review presents an overview of electron ionization time-of-flight mass speclroscopy (EITOFMS), beginning with its early development to the employment of modem high-resolution electron ionization sources. The EITOFMS is demonstrated to be ideally suited for analytical and basic chemical physics

Application of mass spectrometry to the
✍ O. John Semmes; Gunjan Malik; Mike Ward πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 212 KB

## Abstract There has been an impressive emergence of mass spectrometry based technologies applied toward the study of proteins. Equally notable is the rapid adaptation of these technologies to biomedical approaches in the realm of clinical proteomics. Concerted efforts toward the elucidation of th

A review of clinical diagnostic applicat
✍ Bori Shushan πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 560 KB

## Abstract Liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS) technology is emerging as a complementary method to traditional methodology used for clinical applications. Enhanced specificity and high‐throughput capabilities are providing significant benefits to clinical diagnos

Isotope-selective tandem mass spectromet
✍ Lehmann, Wolf D. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 408 KB

The isotopomeric ions of non-isotope-enriched biomolecules generated by nanoelectrospray ionization were selectively fragmented by collision-induced dissociation in a triple-quadrupole mass spectrometer. Using this technique, the inΓ‘uence of heavy isotopes, such as 13C or 18O, on the isotopic patter