A review: Integrin αvβ3-targeted molecular imaging and therapy in angiogenesis
✍ Scribed by Esther H. Lim; Narasimhan Danthi; Mark Bednarski; King C.P. Li
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 110 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1549-9634
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Anti‐angiogenesis is a promising strategy for the treatment of cancer. Integrins, consisting of two noncovalently bound transmembrane α and β subunits, are an important molecular family involved in tumor angiogenesis. The blockade of integrin signaling has been demonstrated to be effici
## Abstract The α~v~β~3~ integrin plays a pivotal role in angiogenesis and tumor metastasis. Angiogenic blood vessels overexpress α~v~β~3~ integrin, as in tumor neovascularization, and α~v~β~3~ integrin expression in other microvascular beds and organs is limited. Therefore, α~v~β~3~ integrin is a
## Abstract Noninvasive molecular imaging of angiogenesis could play a critical role in the clinical management of peripheral vascular disease patients. The α~ν~β~3~‐integrin, a well‐established biomarker of neovascular proliferation, is an ideal target for molecular imaging of angiogenesis. This s