𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Reversible Transition between an α-Helix and a 310-Helix in a Fluorescence-Labeled Peptide

✍ Scribed by Dr. Graham Hungerford; Marta Martinez-Insua; Prof. David J. S. Birch; Dr. Barry D. Moore

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
430 KB
Volume
35
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

First homo-peptides undergoing a reversi
First homo-peptides undergoing a reversible 310-helix/α-helix transition: Critical main-chain length
✍ Alessandro Moretto; Fernando Formaggio; Bernard Kaptein; Quirinus B. Broxterman; 📂 Article 📅 2008 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 183 KB

## Abstract The difference in length between the more elongated peptide 3~10~‐helix and the more compact α‐helix is about 0.4 Å/residue. This property makes the 3~10~‐/α‐helix reversible conversion very promising as a molecular switching tool between the N‐ and C‐terminal functions of a peptide bac

Slow tert-butyl ester acidolysis and pep
Slow tert-butyl ester acidolysis and peptide 310-helix to α-helix transition in HFIP solution
✍ Alessandro Moretto; Marco Crisma; Fernando Formaggio; Bernard Kaptein; Quirinus 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 136 KB

We have already shown by CD and NMR techniques that the terminally protected homo-octapeptides Z (and Ac)-[L-(aMe)Val] 8 -OtBu undergo a slow and irreversible 3 10 -helix to a-helix transition when dissolved in 1,1,1,3,3,3-hexafluoroisopropanol. In the present work, we find by HPLC and CD that under

Design and synthesis of 3α-helix peptide
Design and synthesis of 3α-helix peptides forming a cavity for a fluorescent ligand
✍ Ikuo Obataya; Seiji Sakamoto; Akihiko Ueno; Hisakazu Mihara 📂 Article 📅 2001 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 134 KB

As a model of receptor protein, a series of 3␣-helix bundle peptides constructed on a template peptide were designed so as to possess a hydrophobic cavity. The size of cavity was modulated by simple replacements of Leu residues to Ala residues in the hydrophobic core. Binding abilities to 8-anilino-

Enthalpy distribution for the α-helix/ra
Enthalpy distribution for the α-helix/random coil transition in a model peptide: A study of two-state behavior
✍ Douglas Poland 📂 Article 📅 2001 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 105 KB 👁 1 views

We use heat capacity data of Taylor et al. to calculate the enthalpy distribution of a model peptide using the moments/maximum-entropy method. The peptide was designed with small covalent loops at both ends of the molecule to nucleate ␣-helix thus giving a system that would be expected to show a hel

Chain conformation in polyretropeptides
Chain conformation in polyretropeptides III: Design of a 310 helix using α,α-dialkylated amino acids and retropeptide bonds
✍ Carlos Alemán 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB 👁 1 views

Computer simulations have been used to design a polypeptide with a 3 10 helix conformation. The study has been been performed taking advantage of the intrinsic helix forming tendency of ␣-Aminoisobutyric acid. In order to avoid the formation of the ␣ helix, which is the other common helical conforma