๐”– Bobbio Scriptorium
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A research report on the anti-fatigue effects of magnesium pemoline

โœ Scribed by Maressa Hecht Orzack; Constance L. Taylor; Conan Kornetsky

Book ID
104759704
Publisher
Springer
Year
1968
Tongue
English
Weight
258 KB
Volume
13
Category
Article
ISSN
0033-3158

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โœฆ Synopsis

The effects of magnesium pemoline were compared to those of caffeine and methylphenidate on the performance of a nonmotivated task which required continuous attention over a two hour testing period. The drug treatment consisted of: 25 or 50 mg magnesium pemoline, 100 or 200 mg caffeine, 15 mg methylphcnidate or a placebo. Ten unhospitalized volunteers were each tested six times, once on each treatment. The significant increase in errors which occurcd under placebo conditions did not occur with 50 rag magnesium pemoline, or 200 mg caffeine or 15 mg methylphenidate. These results support the contention of others that magnesium pemoline acts as a nonspecific CNS stimulant.

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Magnesium pemoline: Effects of a broad r
Magnesium pemoline: Effects of a broad range of doses on water maze performance
โœ James E. McCarroll; Susan F. Korbel ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› Springer ๐ŸŒ English โš– 557 KB

60 rats were given doses of 20, 60 or 100 mg/kg of magnesium pemoline or a placebo. They were tested (1 trial a day) for 21 days of drug treatment and for 10 days of no treatment. It was found that drug-treated animals had a significantly lower total time in the maze on some days of the experiment;