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A replication-incompetent virus possessing an uncleavable hemagglutinin as an influenza vaccine

✍ Scribed by Hiroaki Katsura; Kiyoko Iwatsuki-Horimoto; Satoshi Fukuyama; Shinji Watanabe; Saori Sakabe; Yasuko Hatta; Shin Murakami; Masayuki Shimojima; Taisuke Horimoto; Yoshihiro Kawaoka


Book ID
118503216
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
848 KB
Volume
30
Category
Article
ISSN
0264-410X

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✍ Hideki Hasegawa; Takeshi Ichinohe; Peter Strong; Izumi Watanabe; Satoshi Ito; Sh πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 106 KB

## Abstract Chitin in the form of microparticles (chitin microparticles, CMP) has been demonstrated to be a potent stimulator of macrophages, promoting T‐helper‐1 (Th1) activation and cytokine response. In order to examine the mucosal adjuvant effect of CMP co‐administered with influenza hemaggluti