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Construction of CELO recombinant adenoviruses expressing avian type an influenza virus hemagglutinin gene and its use as vaccine against avian influenza virus type a H5N1 and H7N1

✍ Scribed by I. L. Tutykhina; M. I. Shul’pin; I. A. Chvala; M. M. Shmarov; D. Yu. Logunov; L. O. Shcherbakova; M. A. Volkova; N. S. Mudrak; A. V. Borisov; V. V. Drygin; B. S. Naroditskii; A. L. Gintsburg


Book ID
111498317
Publisher
Allerton Press, Inc.
Year
2011
Tongue
English
Weight
172 KB
Volume
26
Category
Article
ISSN
0891-4168

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## Abstract The hemagglutinin (HA) of influenza A virus plays an essential role in mediating the entry of the virus into host cells. Here, recombinant full‐length HA5 protein from a H5N1 isolate (A/chicken/hatay/2004(H5N1)) was expressed and purified from the baculovirus‐insect cell system. As expe