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A replicating module as the unit of mitochondrial structure and functioning

✍ Scribed by Roderick A Capaldi; Robert Aggeler; Robert Gilkerson; George Hanson; Michelle Knowles; Andrew Marcus; Daciana Margineantu; Michael Marusich; James Murray; Devin Oglesbee; S.James Remington; Rodrigue Rossignol

Book ID
117046509
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
202 KB
Volume
1555
Category
Article
ISSN
0005-2728

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Initiation of replication of the linear mitochondrial DNA from Paramecium occurs at a unique cross-linked terminus of the monomer molecule. Dimer length molecules, containing head-to-head monomers, are replicative intermediates. Previous studies have been with cloned dimer initiation region fragment

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✍ I. Lazdins; D. Cummings πŸ“‚ Article πŸ“… 1984 πŸ› Springer-Verlag 🌐 English βš– 633 KB

Replication of mitochondrial DNA in Paramecium aurelia involves the formation of a covalent crosslink at one end of this linear molecule and proceeds unidirectionally, producing a dimer consisting of two head to head monomers. The initiation regions within the dimer molecules have been sequenced and