A Reinvestigation of the α-Alkylation of 4-Monosubstituted 2-phenyloxazol-5(4H)-ones (‘azlactones’): A general entry into highly functionalized α,α-disubstituted α-amino acids

A facile synthesis of 2-alkyl-3-α-carbox

A facile synthesis of 2-alkyl-3-α-carboxy-α-styryl/heterylvinyl quinazolin-4(3H)-ones and 3-arylidene/heterylmethylidene-4-aroyl-1H-[1,4]benzodiazepine-2,5(3H,4H)-diones and their transformation into novel heterocyclyl and heterocyclo analogues

✍ Poonam Gupta; Archana Sharma; R. L. Sharma 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 604 KB

## Abstract Condensation of 2‐methyl‐/2‐ethyl‐ and 2‐phenyl‐/p‐tolyl‐4‐arylidene‐/heterylmethylidene‐2‐oxazolin‐5‐ones (γ‐azlactones) **2** with o‐aminobenzamide **1** in acetic acid resulted in the formation of two entirely different heterocyclic systems, differently substituted quinazoline compou

Highly regio- and stereoselective alkyla

Highly regio- and stereoselective alkylation of nucleophilic glycine equivalents with carbonates of allylic α-hydroxyphosphonates: A convenient route to racemic 2-amino-5-phosphono-4-pentenoic acids

✍ Öhler, Elisabeth ;Kanzler, Silvia 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 31 KB

Asymmetric Synthesis with 6-tert-Butyl-5

Asymmetric Synthesis with 6-tert-Butyl-5-methoxy-6-methyl-3,6-dihydro-2H-1,4-oxazin-2-one as a New Chiral Glycine Equivalent: Preparation of Enantiomerically Pure α-Tertiary and α-Quaternary α-Amino Acids.

✍ Claus-Juergen Koch; Sona Simonyiova; Joerg Pabel; Annerose Kaertner; Kurt Polbor 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 349 KB 👁 1 views

Asymmetric Synthesis with 6-tert-Butyl-5

Asymmetric Synthesis with 6-tert-Butyl-5-methoxy-6-methyl-3,6-dihydro-2H-1,4-oxazin-2-one as a New Chiral Glycine Equivalent: Preparation of Enantiomerically Pure α-Tertiary and α-Quaternary α-Amino Acids

✍ Claus-Jürgen Koch; Soňa Šimonyiová; Jörg Pabel; Annerose Kärtner; Kurt Polborn; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

ChemInform Abstract: (4R,5S)-1,5-Dimethy

ChemInform Abstract: (4R,5S)-1,5-Dimethyl-4-phenylimidazolidin-2-one as a Chiral Auxiliary for the Diastereoselective Alkylation of a New Iminic Glycine Derivative: Practical Asymmetric Synthesis of α-Amino Acids.

✍ G. GUILLENA; C. NAJERA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Functionalization of (2S)-Isopropyl-5-io

Functionalization of (2S)-Isopropyl-5-iodo-2,3-dihydro-4(H)-pyrimidin-4-ones by a Suzuki–Miyaura Cross-Coupling Reaction Using Aryltrifluoroborate Salts: Convenient Enantioselective Preparation of α-Substituted β-Amino Acids

✍ Hélio A. Stefani; Monica F. Z. J. Amaral; Gloria Reyes-Rangel; Jorge Vargas-Capo 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 565 KB

## Abstract A simple protocol for the Pd(OAc)~2~‐catalyzed cross‐coupling reaction of 1‐benzoyl‐(2__S__)‐isopropyl‐5‐iodo‐2,3‐dihydro‐4(__H__)‐pyrimidin‐4‐ones with potassium aryltrifluoroborates was developed. The reaction is performed at 110 °C with a ligand‐free catalyst. In all cases, complete

A Reinvestigation of the α-Alkylation of 4-Monosubstituted 2-phenyloxazol-5(4H)-ones (‘azlactones’): A general entry into highly functionalized α,α-disubstituted α-amino acids

✦ Synopsis