A reinvestigation of 1,2-dihydropyridine formation by condensation of aldehydes with aniline: revision of a structural assignment
β Scribed by Grant Krow; Edward Michener; Kermit C. Ramey
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 171 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract In contrast to previous reports, 4βethoxyβ1,1,1βtrifluoroβ3βbutenβ2βone (**1**) was observed to react with methylhydrazine (**2**) in refluxing ethanol to yield 1βmethylβ3β(trifluoromethyl)pyrazole (**6**) and 4,5βdihydroβ1βmethylβ5β(trifluoromethyl)pyrazolβ5βol (**4**). The later compo
The structure of the product obtained by reacting the 1,4-dihydropyridine 6 with pyridinium bromide perbromide has been confirmed by NMR spectroscopy as the I-bromomethyl derivative 7 and its reaction with a range of nucleophiles has been studied.