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A recyclable CuO-catalyzed synthesis of 4(3H)-quinazolinones

โœ Scribed by Zhan, Dan; Li, Tianbin; Wei, Haidong; Weng, Wen; Ghandi, Khashayar; Zeng, Qingle

Book ID
120335944
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
303 KB
Volume
3
Category
Article
ISSN
2046-2069

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One-step synthesis of 4(3H)-quinazolinon
One-step synthesis of 4(3H)-quinazolinones
โœ Martin J Deetz; Jeremiah P Malerich; Alicia M Beatty; Bradley D Smith ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 103 KB

2-Fluoro substituted benzoyl chlorides undergo cyclocondensation with 2-amino-N-heterocycles to form 4(3H)-quinazolinones. The reaction proceeds in moderate yields with different combinations of benzoyl chlorides and 2-amino-N-heterocycles. The products generally precipitate from the reaction mixtur