A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer
β Scribed by L.K Borysiewicz; A Fiander; M Nimako; S Man; G.W.G Wilkinson; D Westmoreland; A.S Evans; M Adams; S.N Stacey; M.E.G Boursnell; E Rutherford; J.K Hickling; S.C Inglis
- Book ID
- 118561150
- Publisher
- The Lancet
- Year
- 1996
- Tongue
- English
- Weight
- 665 KB
- Volume
- 347
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
Tissue from I I cases of cervical cancer positive for human papillomavirus (HPV) type I 6 DNA and 69 pelvic lymph nodes from the same patients were examined for HPV 16 DNA and mRNA from the E6/E7 genes. Five of the tumors were squamom, 3 adeno-and 3 adenosquamous carcinoma. From the primary tumors a
Sera from I 18 women of 33 to over 90 years of age, with or without a history of cervical squamous-cell carcinoma, were examined for the presence of antibodies to HPV-6b, HPV-I6 and HPV-18 LI, U, E4, and E7 gene products by the use of bacterially derived P-Gal fusion proteins and Western-blot analys