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A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation

✍ Scribed by Wülfing, C.

Book ID
121160430
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
424 KB
Volume
282
Category
Article
ISSN
0036-8075

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## Background: Vav is a guanine-nucleotide exchange factor for the rho-like small gtpases rhoa, rac1 and cdc42, which regulate cytoskeletal reorganization and activation of stress-activated protein kinases (sapk/jnks). vav is expressed in hematopoietic cells and is phosphorylated in t and b cells f