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A Reappraisal of the Stereoselective Metabolism of Nicotine to Nicotine-l'- N -oxide

โœ Scribed by Testa, Bernard; Jenner, Peter; Beckett, Arnold H.; Gorrod, John W.


Book ID
120683110
Publisher
Informa plc
Year
1976
Tongue
English
Weight
214 KB
Volume
6
Category
Article
ISSN
0049-8254

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Nicotine-iminium ions -Trans-3"-hydroxycotinine -5'-hydroxycotinine It has long been generally accepted that the most important pathway in the oxidative degradation of nicotine in humans is oxidation at the ~C atom in the 5' position of the pyrrolidine ring of nicotine. This attack is the origin of