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A Rapid Total Synthesis of Spirotryprostatin B: Proof of Its Relative and Absolute Stereochemistry

✍ Scribed by Franz von Nussbaum; Samuel J. Danishefsky


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
116 KB
Volume
112
Category
Article
ISSN
0044-8249

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Determination of Relative and Absolute Stereochemistry of Cephalosporolide D and Its Enantioselective Total Synthesis. -The title compound (XI) is synthesized in an efficient approach via an aldol reaction of (II) and (III) as key step. (R)-(I) is obtained from commercially available methyl (R)-3-h