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A Rapid Three-Component MgI 2 -Mediated Synthesis of 3,3-Pyrollidinyl Spirooxindoles

✍ Scribed by Helan, Victoria; Mills, Allie; Drewry, David; Grant, Daniel

Book ID
120442509
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
866 KB
Volume
75
Category
Article
ISSN
0022-3263

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✍ NΓΊria Mont; Jordi TeixidΓ³; JosΓ© I Borrell; C.Oliver Kappe πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 116 KB

A new, high yield multicomponent reaction providing multifunctionalized pyrido [2,3-d]pyrimidines in a microwaveassisted one-pot cyclocondensation of a,b-unsaturated esters, amidine systems and malononitrile (or ethyl cyanoacetate) is described (the 'Victory' reaction).