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A three-component synthesis of pyrido[2,3-d]pyrimidines

✍ Scribed by Núria Mont; Jordi Teixidó; José I Borrell; C.Oliver Kappe

Book ID: 104253954
Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 116 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01306-6

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✦ Synopsis

A new, high yield multicomponent reaction providing multifunctionalized pyrido [2,3-d]pyrimidines in a microwaveassisted one-pot cyclocondensation of a,b-unsaturated esters, amidine systems and malononitrile (or ethyl cyanoacetate) is described (the 'Victory' reaction).

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