✦ LIBER ✦

A rapid mild and efficient method of thioacetalization using anhydrous iron(III) chloride dispersed on silica gel

✍ Scribed by Harish K. Patney

Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 131 KB
Volume: 32
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79696-1

No coin nor oath required. For personal study only.

✦ Synopsis

Carbonyl compounds are rapidly thioacetalized in near quantitative yields by using anhydrous iron(lII) chloride dispersed on silica gel at room temperature.

The conversion of carbonyl compounds to the cyclic dithioacetals constitutes an important part of many organic synthetic transformationsi.

Dithioacetals are also useful in organic synthesis as acyl carbanion cquivulents2~ Numerous methods that are reported for this conversion include the use of pmtic acids, Lewis acids and some silicon reagents. la More recently Nafion-H catatysta, silica gel treated with thionyl chloride4

📜 SIMILAR VOLUMES

A New, Efficient and Environmentally Ben

A New, Efficient and Environmentally Benign Protocol for the Synthesis of 1,5-Benzodiazepines using Cerium(III) Chloride/Sodium Iodide Supported on Silica Gel

✍ Gowravaram Sabitha; G. S. Kiran Kumar Reddy; K. Bhaskar Reddy; N. Mallikarjuna R 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB 👁 2 views

## Abstract A novel and green approach has been described for the synthesis of 2,3‐dihydro‐1__H__‐1,5‐benzodiazepines from __o__‐phenylenediamines and ketones using cerium(III) chloride/sodium iodide supported on silica gel under mild and heterogeneous conditions. The reactions are carried out at r