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A New, Efficient and Environmentally Benign Protocol for the Synthesis of 1,5-Benzodiazepines using Cerium(III) Chloride/Sodium Iodide Supported on Silica Gel

✍ Scribed by Gowravaram Sabitha; G. S. Kiran Kumar Reddy; K. Bhaskar Reddy; N. Mallikarjuna Reddy; J. S. Yadav


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
105 KB
Volume
346
Category
Article
ISSN
1615-4150

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✦ Synopsis


Abstract

A novel and green approach has been described for the synthesis of 2,3‐dihydro‐1__H__‐1,5‐benzodiazepines from o‐phenylenediamines and ketones using cerium(III) chloride/sodium iodide supported on silica gel under mild and heterogeneous conditions. The reactions are carried out at room temperature without using any organic solvent.