𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Rapid Method of Screening Blood and Urine Samples for Narcotic Analgesics

✍ Scribed by Win Pe

Publisher
Elsevier
Year
1983
Tongue
English
Weight
442 KB
Volume
23
Category
Article
ISSN
0015-7368

No coin nor oath required. For personal study only.

✦ Synopsis

A simple, rapid method for detection of heroin and its metabolites in blood and urine is described. The technique employs alkaline hydrolysis in an autoclave for 15 minutes followed by two-dimensional TLC using ethyl acetate:methanol:ammonia (85 : 10 :5) and ethanol :dioxane :benzene :ammonia (5 :40 5 0 :5) as developing solvent systems. Visualization of spots is by ferric chloride/ferricyanide spray. Incomplete hydrolysis of the alcoholic 6-acetyl morphine metabolite was found, aiding reliable identification. No dealkylation of codeine occurred during the hydrolysis step.

πŸ“œ SIMILAR VOLUMES

Rapid screening method for polymorphism
Rapid screening method for polymorphism of group A apolipoproteins
✍ Bouchra Harake; Patrick S. M. Caines; Dr. Roger J. Thibert πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 605 KB

## Abstract Polymorphism of apolipoproteins Al and All (ap Al and apo All) can be easily investigated in plasma by a simple method involving a 30‐min incubation of EDTA plasma in the presence of urea, dithiothreitol, and Nonidet P‐40 followed by subsequent isoelectric focusing (IEF). The sample (2

A simple and rapid procedure for the dir
A simple and rapid procedure for the direct detection of cytomegalovirus in urine samples
✍ M. P. Landini; M. X. Guan; A. Ripalti; T. Lazzarotto; M. La Placa; B. Trevisani πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 358 KB πŸ‘ 1 views

## Abstract We compared cytomegalovirus (CMV) isolation in tissue culture and viral DNA detection by DNA:DNA hybridization in 60 clinical urine samples concentrated by different procedures. Our results showed that urine concentration by filtration is the easiest and quickest procedure allowing furt