A rapid computer analysis for multicomponent DNA reassociation kinetics
β Scribed by D.I.C. Kells; N.A. Straus
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 553 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0003-2697
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β¦ Synopsis
An iterative program, Gaushaus, has been adapted to analyze complex DNA reassociation kinetics. With valid experimental data, rapid convergence to a solution is always achieved by this program even when the starting parameters are grossly in error. The output of the program also includes useful statistical information.
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Kinetic of reassociation of short DNA fragments were measured in eight ground squirrel species: Citellus undulatus, C. parryL C. relictus, C. dauricus, C. citellus, C. pygmaeus, C. fulvus and C. major. It was shown that 30-50% of their genome were represented by repeated sequences forming three kine
ANALKIN(AGDC) is a multipurpose computational program that uses a robust unconstrained optimization algorithm (AGDC) for the resolution of Static and Dynamic multicomponent mixtures (SMM and DMM, respectively) and for the validation of kinetic models. It can be applied for the determination of (a) c